A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Klinikum der LMU Muenchen 80366 Muenchen (Bayern) GermanyRekrutierend» Google-MapsUniversity of Illinois Chicago 60612 Chicago United StatesRekrutierend» Google-MapsNorton Cancer Institute - Brownsboro 40241 Louisville United StatesRekrutierend» Google-MapsUniversity of New Mexico Cancer Center 87131 Albuquerque United StatesRekrutierend» Google-MapsMemorial Sloan Kettering Cancer Center 10065 New York United StatesRekrutierend» Google-MapsDuke University 27710 Durham United StatesRekrutierend» Google-MapsUniversity of Pittsburgh Medical Center 15232 Pittsburgh United StatesRekrutierend» Google-MapsUniversity of Tennessee Medical Center Knoxville 37920 Knoxville United StatesRekrutierend» Google-MapsHospital Britanico de Buenos Aires C1280AEB Caba ArgentinaRekrutierend» Google-MapsInstituto Alexander Fleming C1426ANZ Capital Federal ArgentinaRekrutierend» Google-MapsInstituto Argentino de Diagnostico y Tratamiento IADT C1012AAR Ciudad Autónoma de Buenos Aires ArgentinaRekrutierend» Google-MapsHospital Italiano de La Plata B1900AUR La Plata ArgentinaRekrutierend» Google-MapsFundacion Ars Medica 4600 San Salvador de Jujuy ArgentinaRekrutierend» Google-MapsClinica Viedma 8500 Viedma ArgentinaRekrutierend» Google-MapsSanatorio Parque SA 2000 Rosario ArgentinaRekrutierend» Google-MapsCentro Oncologico Korben 1426 Buenos Aires ArgentinaRekrutierend» Google-MapsFundacion Centro Oncológico Riojano Integral para la Investigación y Prevención del Cáncer F5300COE La Rioja ArgentinaRekrutierend» Google-MapsCentro de Diagnostico Investigacion y Tratamiento 4400 Salta ArgentinaRekrutierend» Google-MapsCampbelltown Hospital 2560 Campbelltown AustraliaRekrutierend» Google-MapsConcord Repatriation General Hospital 2139 Concord AustraliaRekrutierend» Google-MapsGenesisCare -North Shore Oncology 2065 St Leonards AustraliaRekrutierend» Google-MapsCalvary Mater Newcastle Hospital 2298 Waratah AustraliaRekrutierend» Google-MapsToowoomba Hospital 4350 Toowoomba AustraliaRekrutierend» Google-MapsPrincess Alexandra Hospital 4102 Woolloongabba AustraliaRekrutierend» Google-MapsCancer Research South Australia 5000 Adelaide AustraliaRekrutierend» Google-MapsPeter MacCallum Cancer Centre 3000 Melbourne AustraliaRekrutierend» Google-MapsThe Alfred Hospital 3004 Melbourne AustraliaRekrutierend» Google-MapsMedizinische Universitaet Graz 8036 Graz AustriaRekrutierend» Google-MapsKlinikum Klagenfurt am Woerthersee 9020 Klagenfurt AustriaRekrutierend» Google-MapsUniversitaetsklinikum Krems 3500 Krems AustriaRekrutierend» Google-MapsLandeskrankenhaus Salzburg 5020 Salzburg AustriaRekrutierend» Google-MapsChirec - Delta Ziekenhuis 1160 Auderghem BelgiumRekrutierend» Google-MapsAlgemeen Ziekenhuis Maria Middelares 9000 Gent BelgiumRekrutierend» Google-MapsUniversitair Ziekenhuis Leuven - Campus Gasthuisberg 3000 Leuven BelgiumRekrutierend» Google-MapsCentre Hospitalier Regional de la Citadelle 4000 Liège BelgiumRekrutierend» Google-MapsAlgemeen Ziekenhuis Sint-Maarten 2800 Mechelen BelgiumRekrutierend» Google-MapsHospital Sirio Libanes 70200-730 Brasilia BrazilRekrutierend» Google-MapsCentro de Tratamento Oncologico - Cto 66053-000 Belem BrazilRekrutierend» Google-MapsInstituto de Medicina Integral Professor Fernando Figueira - Imip 50070-550 Recife BrazilRekrutierend» Google-MapsHospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul 90610-000 Porto Alegre BrazilRekrutierend» Google-MapsCentro de pesquisa em oncologia Hospital Ana Nery 96835-090 Santa Cruz do Sul BrazilRekrutierend» Google-MapsCatarina Pesquisa Clinica 88301-220 Itajaí BrazilRekrutierend» Google-MapsFundacao Pio 12 Hospital de Amor de Barretos 14784-400 Barretos BrazilRekrutierend» Google-MapsSanta Casa de Misericordia de Santos - Iscms 11075-900 Santos BrazilRekrutierend» Google-MapsBeneficencia Portuguesa de Sao Paulo - Bp 01323-900 Sao Paulo BrazilRekrutierend» Google-MapsFundacao Antonio Prudente 01509-900 Sao Paulo BrazilRekrutierend» Google-MapsOncoclinicas Rio de Janeiro S A 22250-905 Rio de Janeiro BrazilRekrutierend» Google-MapsInstituto de Ensino e Pesquisa Sao Lucas Iep Sao Lucas 01236-030 São Paulo BrazilRekrutierend» Google-MapsInstituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira Icesp 01246-000 São Paulo BrazilRekrutierend» Google-MapsMultiprofile Hospital for Active Treatment - Uni Hospital OOD 4500 Panagyurishte BulgariaRekrutierend» Google-MapsAcibadem City Clinic University Multiprofile Hospital for Active Treatment Tokuda EAD 1407 Sofia BulgariaRekrutierend» Google-MapsUniversity Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD 1527 Sofia BulgariaRekrutierend» Google-MapsQueen Elizabeth II, Health Sciences Centre B3H 1V7 Halifax CanadaRekrutierend» Google-MapsSunnybrook Research Institute Sunnybrook Health Sciences Centre M4N 3M5 Toronto CanadaRekrutierend» Google-MapsMcGill University Health Centre Glen Site H4A 3J1 Montreal CanadaRekrutierend» Google-MapsCIUSSS - du Nord-de-lIle-de-Montreal / Hopital Sacre-Coeur de Montreal H4J 1C5 Montreal CanadaRekrutierend» Google-MapsInstitut Universitaire de cardiologie et de pneumologie de Quebec G1V 4G5 Quebec City CanadaRekrutierend» Google-MapsJames Lind Centro de Investigacion del Cancer 4800827 Temuco ChileRekrutierend» Google-MapsClinica CIDO 4810218 Temuco ChileRekrutierend» Google-MapsOrlandi Oncologia 7500713 Santiago ChileRekrutierend» Google-MapsFundacion Arturo Lopez Perez 7500836 Santiago ChileRekrutierend» Google-MapsBiocinetic 8330336 Santiago ChileRekrutierend» Google-MapsCentro de Investigacion del Maule 346000 Talca ChileRekrutierend» Google-MapsGuangdong Provincial Peoples Hospital 510080 Guangzhou ChinaRekrutierend» Google-MapsCancer Hospital of Shantou University Medical College 515031 Shantou ChinaRekrutierend» Google-MapsLiuzhou Peoples Hospital 545006 Liuzhou ChinaRekrutierend» Google-MapsGuangxi Medical University Cancer Hospital 530021 Nanning ChinaRekrutierend» Google-MapsThe First Affiliated Hospital of Henan University of Science And Technology 471003 Luoyang ChinaRekrutierend» Google-MapsXiangyang Central Hospital 441021 Xiangyang ChinaRekrutierend» Google-MapsThe Second Xiangya Hospital of Central South University 410011 Changsha ChinaRekrutierend» Google-MapsNanjing Drum Tower Hospital 210008 Nanjing ChinaRekrutierend» Google-MapsJiangxi Cancer Hospital 330029 Nanchang ChinaRekrutierend» Google-MapsThe First Affiliated Hospital of Nanchang University 330209 Nanchang ChinaRekrutierend» Google-MapsLinyi Peoples Hospital 276002 Linyi ChinaRekrutierend» Google-MapsWest China Hospital of Sichuan University 611135 Chengdu ChinaRekrutierend» Google-MapsSir Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine 310016 Hangzhou ChinaRekrutierend» Google-MapsNantong Tumor Hospital 226361 Nantong ChinaRekrutierend» Google-MapsBeijing Chest Hospital, Capital Medical University 101149 Beijing ChinaRekrutierend» Google-MapsSociedad de Oncologia y Hematologia del Cesar 200001 Valledupar ColombiaRekrutierend» Google-MapsFakultni nemocnice Brno 625 00 Brno CzechiaRekrutierend» Google-MapsFakultni nemocnice Olomouc 779 00 Olomouc CzechiaRekrutierend» Google-MapsFakultni nemocnice Plzen 305 99 Plzen CzechiaRekrutierend» Google-MapsAarhus Universitetshospital 8200 Aarhus N DenmarkRekrutierend» Google-MapsRegionshospitalet Godstrup 7400 Herning DenmarkRekrutierend» Google-MapsRigshospitalet 2100 Kobenhavn DenmarkRekrutierend» Google-MapsSonderborg Sygehus 6400 Sonderborg DenmarkRekrutierend» Google-MapsCentre Hospitalier Régional Universitaire de Besançon, Hôpital Jean Minjoz 25030 Besancon cedex FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire Ambroise Pare 92104 Boulogne-Billancourt FranceRekrutierend» Google-MapsCentre Hospitalier Intercommunal de Créteil 94010 Créteil FranceRekrutierend» Google-MapsCentre Hospitalier - Le Mans 72000 Le Mans FranceRekrutierend» Google-MapsCentre Hospitalier Régional Universitaire de Lille - Institut Coeur Poumon 59037 Lille Cedex FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire Nord 13915 Marseille Cedex 20 FranceRekrutierend» Google-MapsCentre de Cancerologie du Grand Montpellier-Clinique Clementville 34070 Montpellier FranceRekrutierend» Google-MapsHopital Universitaire Caremeau 30029 Nimes cedex 9 FranceRekrutierend» Google-MapsHopital Tenon 75020 Paris Cedex 20 FranceRekrutierend» Google-MapsInstitut Curie 75005 Paris FranceRekrutierend» Google-MapsGroupe Hospitalier Paris Saint Joseph 75014 Paris FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire de Bordeaux - Hopital Haut Leveque 33604 Pessac Cedex FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire de Poitiers - Hopital la Miletrie 86021 Poitiers Cedex FranceRekrutierend» Google-MapsCentre Hospitalier de Cornouaille 29000 Quimper FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire de Reims - Hôpital Maison blanche 51092 Reims Cedex FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire de Rennes - Hopital Pontchaillou 35033 Rennes FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire de Rouen - Hopital Charles Nicolle 76031 Rouen Cedex FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire de Strasbourg - Nouvel Hopital Civil 67091 Strasbourg Cedex FranceRekrutierend» Google-MapsHopital d instruction des armees sainte anne 83800 Toulon FranceRekrutierend» Google-MapsCentre Hospitalier Universitaire de Toulouse - Hopital Larrey 31059 Toulouse Cedex 9 FranceRekrutierend» Google-MapsCentre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau 37044 Tours Cedex 9 FranceRekrutierend» Google-MapsHopital Nord-Ouest Villefranche 69400 Villefranche Sur Saone Cedex FranceRekrutierend» Google-MapsGustave Roussy 94805 Villejuif FranceRekrutierend» Google-Maps251 General Airforce Hospital 11525 Athens GreeceRekrutierend» Google-MapsHenry Dunant Hospital Center 11526 Athens GreeceRekrutierend» Google-MapsAlexandra Hospital 11528 Athens GreeceRekrutierend» Google-MapsAttikon University Hospital 12462 Athens GreeceRekrutierend» Google-MapsMetropolitan Hospital 18547 Athens GreeceRekrutierend» Google-MapsIaso General Clinic 15123 Marousi GreeceRekrutierend» Google-MapsTheagenion Cancer Hospital 54007 Thessaloniki GreeceRekrutierend» Google-MapsAgios Loukas Clinic 55236 Thessaloniki GreeceRekrutierend» Google-MapsEuropean Interbalkan Medical Center 57001 Thessaloniki GreeceRekrutierend» Google-MapsUniversity of Hong Kong, Queen Mary Hospital Hong Kong Hong KongRekrutierend» Google-MapsOrszagos Koranyi Pulmonologiai Intezet 1121 Budapest HungaryRekrutierend» Google-MapsFarkasgyepui Tudogyogyintezet 8582 Farkasgyepu HungaryRekrutierend» Google-MapsMatrai Gyogyintezet 3200 Gyongyos HungaryRekrutierend» Google-MapsFejer Varmegyei Szent Gyorgy Egyetemi Oktato Korhaz 8000 Szekesfehervar HungaryRekrutierend» Google-MapsKomarom-Esztergom Varmegyei Szent Borbala Korhaz 2800 Tatabanya HungaryRekrutierend» Google-MapsReformatus Pulmonologiai Centrum 2045 Torokbalint HungaryRekrutierend» Google-MapsIRCCS Istituto Tumori Giovanni Paolo II 70124 Bari ItalyRekrutierend» Google-MapsAzienda Ospedaliero Universitaria Policlinico G Rodolico - San Marco Presidio Ospedaliero G Rodolico 95123 Catania ItalyRekrutierend» Google-MapsAzienda Ospedaliero Universitaria Careggi 50134 Firenze ItalyRekrutierend» Google-MapsIstituto Romagnolo per lo Studio dei Tumori Dino Amadori 47014 Meldola (FC) ItalyRekrutierend» Google-MapsFondazione IRCCS Istituto Nazionale dei Tumori 20133 Milano ItalyRekrutierend» Google-MapsFondazione IRCCS San Gerardo dei Tintori 20900 Monza (MB) ItalyRekrutierend» Google-MapsAzienda Ospedaliera di Rilievo Nazionale Specialistica dei Colli Monaldi 80131 Napoli ItalyRekrutierend» Google-MapsAzienda Ospedaliero Universitaria Luigi Vanvitelli 80138 Napoli ItalyRekrutierend» Google-MapsAzienda Ospedaliero-Universitaria di Parma 43126 Parma ItalyRekrutierend» Google-MapsAzienda Ospedaliera di Perugia Ospedale Santa Maria della Misericordia 06156 Perugia ItalyRekrutierend» Google-MapsNagoya University Hospital 466-8560 Nagoya-shi JapanRekrutierend» Google-MapsHirosaki University Hospital 036-8563 Hirosaki-shi JapanRekrutierend» Google-MapsChiba Cancer Center 260-8717 Chiba-shi JapanRekrutierend» Google-MapsNational Cancer Center Hospital East 277-8577 Kashiwa-shi JapanRekrutierend» Google-MapsNational Hospital Organization Shikoku Cancer Center 791-0280 Matsuyama-shi JapanRekrutierend» Google-MapsEhime University Hospital 791-0295 Toon-shi JapanRekrutierend» Google-MapsNational Hospital Organization Kyushu Cancer Center 811-1395 Fukuoka-shi JapanRekrutierend» Google-MapsHospital of the University of Occupational and Environmental Health Japan 807-8556 Kitakyushu-shi JapanRekrutierend» Google-MapsKurume University Hospital 830-0011 Kurume-shi JapanRekrutierend» Google-MapsChugoku Central Hospital of Japan Mutual Aid Association of Public School Teachers 720-0001 Fukuyama-shi JapanRekrutierend» Google-MapsNational Hospital Organization Hokkaido Cancer Center 003-0804 Sapporo-shi JapanRekrutierend» Google-MapsKobe Minimally invasive Cancer Center 650-0046 Kobe-shi JapanRekrutierend» Google-MapsTakarazuka City Hospital 665-0827 Takarazuka-shi JapanRekrutierend» Google-MapsKanazawa University Hospital 920-8641 Kanazawa-shi JapanRekrutierend» Google-MapsSt Marianna University Hospital 216-8511 Kawasaki-shi JapanRekrutierend» Google-MapsKanagawa Prefectural Hospital Organization Kanagawa Cancer Center 241-8515 Yokohama-shi JapanRekrutierend» Google-MapsKyoto University Hospital 606-8507 Kyoto-shi JapanRekrutierend» Google-MapsMiyagi Cancer Center 981-1293 Natori-shi JapanRekrutierend» Google-MapsSendai Kousei Hospital 981-0914 Sendai-shi JapanRekrutierend» Google-MapsNiigata Cancer Center Hospital 951-8566 Niigata-shi JapanRekrutierend» Google-MapsOkayama University Hospital 700-8558 Okayama-shi JapanRekrutierend» Google-MapsKansai Medical University Hospital 573-1191 Hirakata-shi JapanRekrutierend» Google-MapsOsaka International Cancer Institute 541-8567 Osaka-shi JapanRekrutierend» Google-MapsKindai University Hospital 589-8511 Osakasayama-shi JapanRekrutierend» Google-MapsNational Hospital Organization Kinki-chuo Chest Medical Center 591-8555 Sakai-shi JapanRekrutierend» Google-MapsSaitama Cancer Center 362-0806 Kitaadachi-gun JapanRekrutierend» Google-MapsShizuoka Cancer Center 411-8777 Sunto-gun JapanRekrutierend» Google-MapsJuntendo University Hospital 113-8431 Bunkyo-ku JapanRekrutierend» Google-MapsThe Cancer Institute Hospital of Japanese Foundation for Cancer Research 135-8550 Koto-ku JapanRekrutierend» Google-MapsTottori University Hospital 683-8504 Yonago-shi JapanRekrutierend» Google-MapsWakayama Medical University Hospital 641-8510 Wakayama-shi JapanRekrutierend» Google-MapsNational Hospital Organization Yamaguchi-Ube Medical Center 755-0241 Ube-shi JapanRekrutierend» Google-MapsNational Cancer Center 10408 Goyang-si Gyeonggi-do Korea, Republic ofRekrutierend» Google-MapsGachon University Gil Hospital 405-835 Incheon Korea, Republic ofRekrutierend» Google-MapsKorea University Anam Hospital 02841 Seoul Korea, Republic ofRekrutierend» Google-MapsAsan Medical Center 05505 Seoul Korea, Republic ofRekrutierend» Google-MapsSamsung Medical Center 06351 Seoul Korea, Republic ofRekrutierend» Google-MapsPauls Stradins Clinical University Hospital 1002 Riga LatviaRekrutierend» Google-MapsRiga East Clinical University Hospital 1079 Riga LatviaRekrutierend» Google-MapsHospital Tengku Ampuan Afzan 25100 Kuantan MalaysiaRekrutierend» Google-MapsPantai Hospital Kuala Lumpur 59100 Kuala Lumpur MalaysiaRekrutierend» Google-MapsUniversity Malaya Medical Centre 59100 Kuala Lumpur MalaysiaRekrutierend» Google-MapsHealth Pharma Professional Research SA de CV 03100 Mexico City MexicoRekrutierend» Google-MapsHospital Civil de Guadalajara Fray Antonio Alcalde 44280 Guadalajara MexicoRekrutierend» Google-MapsOncare CP66220 Monterrey MexicoRekrutierend» Google-MapsActualidad Basada en la Investigación del Cáncer 44680 Guadalajara MexicoRekrutierend» Google-MapsMeander Medisch Centrum 3813 TZ Amersfoort NetherlandsRekrutierend» Google-MapsUniversitair Medisch Centrum Groningen 9713 GZ Groningen NetherlandsRekrutierend» Google-MapsSint Jansdal Ziekenhuis 3844 DG Harderwijk NetherlandsRekrutierend» Google-MapsMaastricht Universitair Medisch Centrum 6229 HX Maastricht NetherlandsRekrutierend» Google-MapsElisabeth-TweeSteden Ziekenhuis 5022 GC Tilburg NetherlandsRekrutierend» Google-MapsIsala Klinieken 8025 AB Zwolle NetherlandsRekrutierend» Google-MapsUniwersytecki Szpital Kliniczny w Bialymstoku 15-540 Bialystok PolandRekrutierend» Google-MapsCentrum Pulmonologii i Torakochirurgii w Bystrej 43-630 Bystra PolandRekrutierend» Google-MapsSzpital Specjalistyczny imienia Ludwika Rydygiera w Krakowie Sp zoo 31-826 Krakow PolandRekrutierend» Google-MapsUniwerystecki Szpital Kliniczny Nr 4 w Lublinie 20-090 Lublin PolandRekrutierend» Google-MapsMed Polonia Sp zoo 60-693 Poznan PolandRekrutierend» Google-MapsWojewodzki Szpital im Sw Ojca Pio w Przemyslu 37-700 Przemysl PolandRekrutierend» Google-MapsNarodowy Instytut Onkologii im Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy 02-781 Warszawa PolandRekrutierend» Google-MapsFundacao Champalimaud 1400-038 Lisboa PortugalRekrutierend» Google-MapsHospital da Luz, SA 1500-650 Lisboa PortugalRekrutierend» Google-MapsUnidade Local de Saude de Santa Maria, EPE - Hospital Pulido Valente 1769-001 Lisboa PortugalRekrutierend» Google-MapsHospital Cuf Tejo 1998-018 Lisboa PortugalRekrutierend» Google-MapsUnidade Local de Saude de Matosinhos, EPE - Hospital Pedro Hispano 4464-513 Matosinhos PortugalRekrutierend» Google-MapsHospital Cuf porto 4100-180 Porto PortugalRekrutierend» Google-MapsInstitutul Oncologic, Prof Dr Alexandru Trestioreanu 022328 Bucuresti RomaniaRekrutierend» Google-MapsSpitalul Universitar de Urgenta Bucuresti 050098 Bucuresti RomaniaRekrutierend» Google-MapsInstitutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca 400015 Cluj Napoca RomaniaRekrutierend» Google-MapsSC Medisprof SRL 400641 Cluj Napoca RomaniaRekrutierend» Google-MapsCentrul de Oncologie Sf Nectarie SRL 200542 Craiova RomaniaRekrutierend» Google-MapsInstitutul Regional de Oncologie Iasi 700483 Iasi RomaniaRekrutierend» Google-MapsSpitalul Municipal Ploiesti 100337 Ploiesti RomaniaRekrutierend» Google-MapsSC Oncomed SRL 300239 Timisoara RomaniaRekrutierend» Google-MapsNational University Hospital 119228 Singapore SingaporeRekrutierend» Google-MapsTan Tock Seng Hospital 308433 Singapore SingaporeRekrutierend» Google-MapsHospital Regional Universitario de Malaga 29011 Malaga SpainRekrutierend» Google-MapsHospital Universitario Virgen del Rocio 41013 Sevilla SpainRekrutierend» Google-MapsHospital Clinico Universitario Lozano Blesa 50009 Zaragoza SpainRekrutierend» Google-MapsHospital Universitario Insular de Gran Canaria 35016 Las Palmas de Gran Canaria SpainRekrutierend» Google-MapsHospital Universitario Marques de Valdecilla 39008 Santander SpainRekrutierend» Google-MapsHospital del Mar 08003 Barcelona SpainRekrutierend» Google-MapsHospital Universitari Vall d Hebron 08035 Barcelona SpainRekrutierend» Google-MapsHospital Clinic i Provincial de Barcelona 08036 Barcelona SpainRekrutierend» Google-MapsHospital de la Santa Creu i Sant Pau 08041 Barcelona SpainRekrutierend» Google-MapsInstitut Catala d Oncologia Hospitalet Hospital Duran i Reynals 08908 Hospitalet de Llobregat SpainRekrutierend» Google-MapsHospital Clinico Universitario de Valencia 46010 Valencia SpainRekrutierend» Google-MapsHospital Universitario Puerta de Hierro Majadahonda 28222 Majadahonda SpainRekrutierend» Google-MapsHospital Clinico San Carlos 28040 Madrid SpainRekrutierend» Google-MapsHospital Universitario La Paz 28046 Madrid SpainRekrutierend» Google-MapsSahlgrenska Universitetssjukhuset 413 45 Goteborg SwedenRekrutierend» Google-MapsGavle Sjukhus 801 87 Gävle SwedenRekrutierend» Google-MapsKantonsspital Aarau 5001 Aarau SwitzerlandRekrutierend» Google-MapsKantonsspital Baden 5404 Baden SwitzerlandRekrutierend» Google-MapsUniversitaetsspital Basel 4031 Basel SwitzerlandRekrutierend» Google-MapsVeterans General Hospital - Taichung 40705 Taichung TaiwanRekrutierend» Google-MapsNational Cheng Kung University Hospital 70403 Tainan TaiwanRekrutierend» Google-MapsNational Taiwan University Hospital 10002 Taipei TaiwanRekrutierend» Google-MapsTaipei Veterans General Hospital 11217 Taipei TaiwanRekrutierend» Google-MapsLinkou Chang Gung Memorial Hospital 33305 Taoyuan TaiwanRekrutierend» Google-MapsKing Chulalongkorn Memorial Hospital 10330 Bangkok ThailandRekrutierend» Google-MapsPhramongkutklao Hospital 10400 Bangkok ThailandRekrutierend» Google-MapsMaharaj Nakorn Chiang Mai Hospital 50200 Chiang Mai ThailandRekrutierend» Google-MapsSrinagarind Hospital 40002 Khon Kaen ThailandRekrutierend» Google-MapsSongklanagarind Hospital 90110 Songkla ThailandRekrutierend» Google-MapsMedical Park Seyhan Hastanesi 01140 Adana TurkeyRekrutierend» Google-MapsGazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi 06560 Ankara TurkeyRekrutierend» Google-MapsAnkara Bilkent Sehir Hastanesi 06800 Ankara TurkeyRekrutierend» Google-MapsAkdeniz Universitesi Tip Fakultesi 07050 Antalya TurkeyRekrutierend» Google-MapsPamukkale Universitesi Tip Fakultesi Hastanesi 20070 Denizli TurkeyRekrutierend» Google-MapsIstanbul Universitesi Cerrahpasa Tip Fakultesi 34098 Istanbul TurkeyRekrutierend» Google-MapsBagcilar Medipol Mega Universite Hastanesi 34214 Istanbul TurkeyRekrutierend» Google-MapsGoztepe Prof Dr Suleyman Yalcin Sehir Hastanesi 34722 Istanbul TurkeyRekrutierend» Google-MapsMarmara Universitesi Tip Fakultesi Hastanesi 34890 Istanbul TurkeyRekrutierend» Google-MapsIzmir Ekonomi Universitesi Medical Point Hastanesi 35575 Izmir TurkeyRekrutierend» Google-MapsQueen Elizabeth Hospital B15 2TH Birmingham United KingdomRekrutierend» Google-MapsRaigmore Hospital IV2 3UJ Inverness United KingdomRekrutierend» Google-MapsNottingham City Hospital NG5 1PB Nottingham United KingdomRekrutierend» Google-MapsTorbay Hospital TQ2 7AA Torquay United KingdomRekrutierend» Google-MapsRoyal Cornwall Hospital TR1 3LQ Truro United KingdomRekrutierend» Google-Maps
1. Progression-free Survival (PFS) (Time Frame - From Baseline up to end of study (EOS) (approximately 5.5 years)): PFS is defined as the time from randomization until the first documentation of radiologic
disease progression or death due to any cause, whichever occurs first. Progression will
be based on Response Evaluation Criteria in Solid Tumors (RECIST) v1.1, per Blinded
Independent Central Review (BICR).
Secondary outcome:
1. Objective Response Rate (ORR) (Time Frame - From Baseline up to EOS (approximately 5.5 years)): Objective response is defined as the best overall response of complete response (CR) or
partial response (PR), based on RECIST v1.1, per BICR.
2. Overall Survival (OS) (Time Frame - From Baseline up to EOS (approximately 5.5 years)): OS is defined as the time from randomization until death due to any cause.
3. Change in Quality-of-Life Questionnaire Core 30 (QLQ-C30) Dyspnea Domain Score (Time Frame - From Baseline to Week 12)
4. Change in Quality-of-Life Questionnaire Lung Cancer 13 (QLQ-LC13) Symptoms of Dyspnea Subscale (Time Frame - From Baseline to Week 12)
5. Change in QLQ-LC13 Symptoms of Cough Subscale (Time Frame - From Baseline to Week 12)
6. Change in QLQ-LC13 Symptoms of Chest Pain Subscale (Time Frame - From Baseline to Week 12)
7. Change in Physical Function as Measured by QLQ-C30 (Time Frame - From Baseline to Week 12)
8. Change in Global Health Status as Measured by QLQ-C30 (Time Frame - From Baseline to Week 12)
9. Progression-free Survival 2 (PFS2) (Time Frame - From Baseline up to EOS (approximately 5.5 years)): PFS2 is defined as the time from randomization to progression per investigator after
initiation of new anticancer therapy or treatment beyond progression (ie, second
progression) or death from any cause, whichever occurs first.
10. Change in QLQ-LC13 Subscale Scores (Time Frame - From Baseline up to EOS (approximately 5.5 years))
11. Change in QLQ-C30 Subscale Scores (Time Frame - From Baseline up to EOS (approximately 5.5 years))
12. Time to Deterioration in QLC-LC13 Subscale Scores (Time Frame - From Baseline to Week 12)
13. Time to Deterioration in QLC-C30 Subscale Scores (Time Frame - From Baseline to Week 12)
14. Change in Summary Scores and Visual Analogue Scale (VAS) Scores (Time Frame - From Baseline up to EOS (approximately 5.5 years)): Measured by EuroQol-5 Dimension (EQ-5D-5L).
15. Duration of Response (Time Frame - From Baseline up to EOS (approximately 5.5 years)): Duration of response is defined as the time from the first documentation of objective
response until the first documentation of disease progression per BICR or death due to
any cause, whichever occurs first.
16. Time to Response (Time Frame - From Baseline up to EOS (approximately 5.5 years)): Defined as the time from randomization to first evidence of PR or CR per BICR.
17. Disease Control (Time Frame - From Baseline up to EOS (approximately 5.5 years)): Defined as CR plus PR plus stable disease based on RECIST v1.1 per BICR.
18. PFS (Time Frame - From Baseline up to EOS (approximately 5.5 years)): Based on investigator tumor assessments per RECIST v1.1.
19. Objective Response (Time Frame - From Baseline up to EOS (approximately 5.5 years)): Based on investigator tumor assessments per RECIST v1.1.
20. Number of Participants With Treatment-Emergent Adverse Events (Time Frame - From Baseline up to EOS (approximately 5.5 years))
21. Number of Participants With Clinically Significant Changes in Vital Signs (Time Frame - From Baseline up to EOS (approximately 5.5 years))
22. Number of Participants With Clinically Significant Changes in Clinical Laboratory Tests (Time Frame - From Baseline up to EOS (approximately 5.5 years))
23. Maximum Plasma Concentration (Cmax) of Sotorasib (Time Frame - Pre-dose Day 1 up to Day 64)
24. Minimum Plasma Concentration (Cmin) of Sotorasib (Time Frame - Pre-dose Day 1 up to Day 64)
25. Area Under The Curve (AUC) of Sotorasib (Time Frame - Pre-dose Day 1 up to Day 64)
Sie können folgenden Inhalt einem Kollegen empfehlen:
"A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)"
Bitte tragen Sie auch die Absenderdaten vollständig ein, damit Sie der Empfänger erkennen kann.
Die mit (*) gekennzeichneten Angaben müssen eingetragen werden!
